IL-21R Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-4855	100 μL

Catalog No. 50-198-4855 Supplier Bioss Supplier No. BS2622R

Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.

Specifications

• Antigen: IL-21R
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Il21r
• Gene Accession No.: Q9HBE5
• Gene Alias: CD360; IL-21 receptor; IL21R; IL-21R; interleukin 21 receptor; Interleukin-21 receptor; LR-beta; Lymphocyte receptor beta; MGC10967; Nilr; Novel cytokine receptor 8; Novel interleukin receptor; NR8; UNQ3121/PRO10273
• Gene Symbols: Il21r
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human IL-21R.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 50615
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG