IL-28 (IFN lambda) Monoclonal Antibody (RN28), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-136-73	Invitrogen™ 14728181	50 μg
50-136-74	Invitrogen™ 14728185	500 μg

Description

Description: This monoclonal RN28 antibody reacts with IL-28 (IFN lambda), a member of the IFN-lambda family which mediates the induction of anti-viral protection in a wide variety of cells. Applications Reported: The RN28 antibody has been reported for use in ELISA capture of mouse IL-28. Applications Tested: This RN28 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse IL-28 in combination with the biotin polyclonal (cat. 13-7282) antibody for detection. A suitable range of concentrations of this antibody for ELISA capture is 1.0-4 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 4000 pg/mL - 30 pg/mL should be included in each ELISA plate. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Specifications

• Antigen: IL-28 (IFN lambda)
• Concentration: 0.5 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Alias: Cytokine Zcyto20; cytokine Zcyto22; EG330496; IFL-1; IFN lambda2; Ifnl2; Ifnl3; IFN-lambda2; IFN-lambda-2; IFN-lambda-3; IFN-lambda-4; IL 28; IL 28 A; Il28; Il28a; IL-28A; Il28b; IL-28B; IL28C; IL-28C; ILN; INF-alpha; INF-lambda; interferon alpha; interferon lambda 2; interferon lambda 3; Interferon lambda2; interferon lambda-2; Interferon lambda-3; interferon, lambda 2; interferon, lambda 3; interferon, lambda 4; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin 28B; interleukin-28A; Interleukin-28B; interleukin-28C; ZCYTO20; ZCYTO22
• Gene Symbols: Ifnl2, Ifnl3
• Primary or Secondary: Primary
• Content And Storage: 4°C

• Clone: RN28
• Applications: ELISA
• Conjugate: Unconjugated
• Host Species: Rat
• Target Species: Mouse
• Gene Accession No.: Q4VK74, Q8CGK6
• Gene ID (Entrez): 330496, 338374
• Isotype: IgG1 κ
• Purification Method: Affinity chromatography
• Product Type: Antibody

For Research Use Only.