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Invitrogen™ IL-32 Polyclonal Antibody
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Catalog No. PIPA520221
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100 μg
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Catalog No. Quantity
PIPA520221 100 μg
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Catalog No. PIPA520221 Supplier Invitrogen™ Supplier No. PA520221
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human spleen tissue lysate. PA5-20221 can be used with blocking peptide PEP-0334.

Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-a, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN-gamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.
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Specifications

Antigen IL-32
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene IL32
Gene Accession No. P24001
Gene Alias IL32; IL-32; IL-32alpha; IL-32beta; IL-32delta; IL-32gamma; ILN; Interleukin; interleukin 32; interleukin-32; interleukin-32 eta; interleukin-32 small; interleukin-32 theta; natural killer cell transcript 4; natural killer cells protein 4; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; Tumor necrosis factor alpha-inducing factor
Gene Symbols IL32
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the carboxy terminus of human IL-32.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9235
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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