IL17RC Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 156481AP150UL

Catalog No. 50-173-0375

Description

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predomitly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

Specifications

• Antigen: IL17RC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IL17RC
• Gene Alias: IL 17 receptor C, IL 17RC, IL 17RL, IL17 RL, IL17RC, IL17Rhom, IL17RL, interleukin 17 receptor C, ZcytoR14
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171095, 84818
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8K4C2, Q8NAC3
• Gene Symbols: Il17rc
• Immunogen: IL17RC Fusion Protein Ag8190
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG