Invitrogen™ IL1R2 Monoclonal Antibody (34141), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523662

Catalog No. PIMA523662

Description

When used in combination with the biotinylated human IL-1 RII affinity purified polyclonal detection antibody in sandwich ELISAs, no significant cross-reactivity or interference was observed with recombinant human (rh) IL-1ra, rhIL-1 RI, recombinant mouse IL-1ra, or recombinant rat IL-1ra.

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.

Specifications

• Antigen: IL1R2
• Classification: Monoclonal
• Conjugate: FITC
• Gene: Il1r2
• Gene Alias: antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 receptor beta chain; IL-1 type II receptor; Il1r2; Il-1r2; IL-1R-2; Il1r-2; IL1R2c; IL1RB; IL-1R-beta; IL-1RT2; IL-1RT-2; ILR2; interleukin 1 receptor type 2; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type 2, membrane form; Interleukin-1 receptor type 2, soluble form; Interleukin-1 receptor type II; mIL-1R2; sIL-1R2; type II interleukin-1 receptor, beta
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 7850
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: 34141
• Formulation: Buffered saline solution with BSA and 0.09% sodium azide
• Gene Accession No.: P27930
• Gene Symbols: Il1r2
• Immunogen: Sf 21-derived recombinant human IL-1 RII Phe14-Glu343 (Ser56Gly and Glu297Gly).
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1