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IMPA1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 165931AP

Catalog No. 50-173-1042


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Description

Description

IMPA1, also known as Myo-inositol monophosphatase 1, is responsible for the procurement of inositol that is required for synthesis of phosphatidylinositol and polyphosphoinositides. IMPA1 exists as a homodimer and has been identified as the pharmacological target for lithium action in the brain. IMPA1 is the principal enzyme of the phosphatidyl inositol signaling pathway, and inhibition of inositol monophosphatase hydrolysis may underlie the anti-manic and anti-depressant actions of Li+. Studies indicate that a variation in the 277 codon coding region of the IMPA1 gene has not been observed in manic-depressive patients, therefore suggesting that polymorphisms or mutations in the noncoding regions of this gene may influence the lithium response in psychiatric patients.
Specifications

Specifications

IMPA1
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O55023, P29218, P97697
IMP 1, IMPA, IMPA1, IMPase 1, Inositol monophosphatase 1
Rabbit
IgG
150 μL
-20°C
Primary
3612, 55980, 83523
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
IMPA1
Liquid
IMPA1
IMPA1 Fusion Protein Ag9632
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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