Invitrogen™ INPP5J Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109861

Catalog No. PIPA5109861

Description

Immunogen sequence: VTWNVGTAMP PDDVTSLLHL GGGDDSDGAD MIAIGLQEVN SMLNKRLKDA LFTDQWSELF MDALGPFNFV LVSSVRMQGV ILLLFAKYYH LPFLRDVQTD CTRTGLGGYW GNKGGVSVRL AAFGHMLCFL NCHLPAHMDK AEQRKDNFQT ILSLQQFQGP GAQGILDHDL VFWFGDLNFR IESYDLHFVK FAIDSDQLHQ LWEKDQLNMA KNTWPILKGF QEGPLNFAPT FKFDVGTNKY DTSAKKRKPA WTDRILWKVK APGGGPSPSG RKSHRLQVTQ HSYRSHMEYT VSDHKPVAAQ F.

Inositol and phosphatidylinositol phosphates are important for numerous cellular processes, including neuronal survival and signal transductions from growth factors, neurotransmitters and G protein coupled receptors. INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP (proline-rich inositol polyphosphate 5-phosphatase), PIB5PA or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate. Expressed in lung, stomach, kidney, brain, small intestine and heart, INPP5J localizes to membrane ruffles, where it may also participate in modulating inositol and phosphatidylinositol polyphosphate-binding proteins. Encoded by a gene located on human chromosome 22, INPP5J undergoes alternative splicing to produce three isoforms.

Specifications

• Antigen: INPP5J
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INPP5J
• Gene Alias: Inositol polyphosphate 5-phosphatase J; inositol polyphosphate-5-phosphatase J; Inpp; INPP5; Inpp5j; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; Pib5pa; Pipp; Proline-rich inositol polyphosphate 5-phosphatase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170835, 171088, 27124
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.09 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P59644, Q15735, Q9JMC1
• Gene Symbols: INPP5J
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-360 of human INPP5J (NP_001002837.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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