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Insulin Antibody (IRDN/805), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NP247727A70 Shop All R&D Systems Products
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Catalog No. NP247727A70 Supplier Novus Biologicals Supplier No. NBP247727AF750
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Description

Mouse Monoclonal Antibody

Insulin Monoclonal specifically detects Insulin in Human, Mouse, Porcine, Bovine, Rabbit, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Insulin
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone IRDN/805
Conjugate Alexa Fluor 750
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
Gene Symbols INS
Host Species Mouse
Immunogen Recombinant Insulin protein (Uniprot: P01308)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 3630
Test Specificity Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Target Species Human, Mouse, Pig, Primate, Rabbit, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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