Insulin Antibody (SPM531), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234780AF350

Catalog No. NB006687

Description

Insulin Monoclonal specifically detects Insulin in Human, Rat, Porcine, Bovine, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Insulin
• Classification: Monoclonal
• Conjugate: Alexa Fluor 350
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: INS
• Immunogen: Full length (1-84 amino acid) Purified pig insulin, conjugated to KLH (Uniprot: P01308)
• Quantity: 0.1 mL
• Research Discipline: Diabetes Research, Immune System Diseases, Immunology, Lipid and Metabolism, Stem Cell Markers
• Test Specificity: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: SPM531
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Rat, Pig, Bovine, Rabbit
• Isotype: IgG1 κ