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Insulin Antibody (SPM531), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NB006687 Shop All R&D Systems Products
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NB006687 0.1 mL
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Catalog No. NB006687 Supplier Novus Biologicals Supplier No. NBP234780AF350
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Description

Mouse Monoclonal Antibody

Insulin Monoclonal specifically detects Insulin in Human, Rat, Porcine, Bovine, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen Insulin
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM531
Conjugate Alexa Fluor 350
Dilution Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
Gene Symbols INS
Host Species Mouse
Immunogen Full length (1-84 amino acid) Purified pig insulin, conjugated to KLH (Uniprot: P01308)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Diabetes Research, Immune System Diseases, Immunology, Lipid and Metabolism, Stem Cell Markers
Primary or Secondary Primary
Test Specificity Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Target Species Human, Rat, Pig, Bovine, Rabbit
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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