Insulin Mouse anti-Human, Mouse, Clone: 4B6A7, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-6632	Proteintech Group Inc 661981IG150UL	150 μL

Description

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.

Specifications

• Antigen: Insulin
• Concentration: 1.23 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: ILPR, INS, Insulin, IRDN
• Gene Symbols: INS
• Isotype: IgG2a
• Purification Method: Protein A
• Product Type: Antibody

• Clone: 4B6A7
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse
• Gene Accession No.: P01308
• Gene ID (Entrez): 3630
• Immunogen: Insulin Fusion Protein Ag8630
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: INS