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Insulin Mouse, Clone: E2-E3 + 2D11-H5 (same as INS04 + INS05), Novus Biologicals™
SDP

Catalog No. NBP234261B Shop All R&D Systems Products
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Catalog No. Quantity
NBP234261B 0.2 mg
NBP234261F 0.02 mg
NBP234261A 0.1 mg
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Catalog No. NBP234261B Supplier Novus Biologicals Supplier No. NBP2342610.2MG

Description

Mouse Monoclonal Antibody

Insulin Monoclonal antibody specifically detects Antigen in Bovine, Human, Mouse, Porcine, Rabbit samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting.

Specifications

Antigen Insulin
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone E2-E3 + 2D11-H5 (same as INS04 + INS05)
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/mlimmunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P01308
Gene Alias IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
Gene Symbols INS
Host Species Mouse
Immunogen Full length (1-84 amino acid) purified pig insulin, conjugated to KLH (E2-E3 and 2D11-H5)
Molecular Weight of Antigen 6 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 3630
Test Specificity Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Target Species Human, Mouse, Pig, Bovine, Rabbit
Content And Storage Store at 4C.
Form Purified
Isotype IgG
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