Integrin alpha L/CD11a Antibody (DF1524), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2446000.2MG

Catalog No. NBP24460002

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

Integrin alpha L/CD11a Monoclonal antibody specifically detects Integrin alpha L/CD11a in Human samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.

Specifications

• Antigen: Integrin alpha L/CD11a
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
• Gene Alias: CD11 antigen-like family member A, CD11a antigen, CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide, integrin alpha-L, integrin gene promoter, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide), Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, lymphocyte function-associated antigen 1
• Host Species: Mouse
• Molecular Weight of Antigen: 180 kDa
• Quantity: 0.2 mg
• Research Discipline: Adaptive Immunity, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Myeloid Cell Markers, Signal Transduction, Stem Cell Markers
• Gene ID (Entrez): 3683
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, SDS-Page, Immunofluorescence
• Clone: DF1524
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: ITGAL
• Immunogen: Human CD11a protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a/C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.
• Content And Storage: Store at 4C.
• Isotype: IgG2b κ

For Research Use Only