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Tocris Bioscience™ Iressa
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Catalog No. 300010
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30-001-0 10 mg
30-005-0 50 mg
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Catalog No. 30-001-0 Supplier Tocris Bioscience™ Supplier No. 3000/10
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Description

Orally active, selective EGFR inhibitor

Iressa is an orally active, selective inhibitor of EGFR tyrosine kinase (IC50 = 23 - 79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. Also inhibits growth of brain metastases in mouse model of non-small cell lung cancer. View information regarding the usage of Iressa for non-clinical studies .

Chemical Identifiers

CAS 184475-35-2
Molecular Formula C22H24ClFN4O3

Specifications

Quantity 10 mg
Formula Weight 446.9
Purity >98%
Molecular Weight (g/mol) 446.91
Chemical Name or Material N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine

Safety and Handling

Recommended Storage Store at Room Temperature
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