IRF3 Mouse anti-Human, Clone: 1E6G8, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 666701IG150UL

Catalog No. 50-173-7087

Description

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, and cytoskeleton reorganization.

Specifications

• Antigen: IRF3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q14653
• Gene Symbols: IRF3
• Immunogen: IRF3 Fusion Protein Ag27223
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 1E6G8
• Conjugate: Unconjugated
• Gene: IRF3
• Gene Alias: interferon regulatory factor 3, IRF 3, IRF3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3661
• Content And Storage: -20°C
• Form: Liquid