IRF3 Mouse anti-Human, Clone: 1E6G8, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-7087	Proteintech Group Inc 666701IG150UL	150 μL

Description

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, and cytoskeleton reorganization.

Specifications

• Antigen: IRF3
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: interferon regulatory factor 3, IRF 3, IRF3
• Gene Symbols: IRF3
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1E6G8
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q14653
• Gene ID (Entrez): 3661
• Immunogen: IRF3 Fusion Protein Ag27223
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: IRF3