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  9. 180310

ITE, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
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448906-42-1
C14H10N2O3S
286.305
KDDXOGDIPZSCTM-UHFFFAOYSA-N
ite,methyl 2-1h-indole-3-carbonyl thiazole-4-carboxylate,methyl 2-1h-indole-3-carbonyl-1,3-thiazole-4-carboxylate,2-1h-indol-3-ylcarbonyl-4-thiazolecarboxylic acid methyl ester,ite cancer,d07izs,the endogeneous ahr ligand,aryl hydrocarbon receptor ligand,ite cancer , ahr pharmaceuticals,methyl2-1h-indole-3-carbonyl thiazole-4-carboxylate
4668801
methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate
COC(=O)C1=CSC(=N1)C(=O)C2=CNC3=CC=CC=C32
This item is not returnable. View return policy
448906-42-1
C14H10N2O3S
286.305
KDDXOGDIPZSCTM-UHFFFAOYSA-N
ite,methyl 2-1h-indole-3-carbonyl thiazole-4-carboxylate,methyl 2-1h-indole-3-carbonyl-1,3-thiazole-4-carboxylate,2-1h-indol-3-ylcarbonyl-4-thiazolecarboxylic acid methyl ester,ite cancer,d07izs,the endogeneous ahr ligand,aryl hydrocarbon receptor ligand,ite cancer , ahr pharmaceuticals,methyl2-1h-indole-3-carbonyl thiazole-4-carboxylate
4668801
methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate
COC(=O)C1=CSC(=N1)C(=O)C2=CNC3=CC=CC=C32

Description

Endogenous agonist for the transcription factor aryl hydrocarbon receptor

Endogenous aryl hydrocarbon receptor (AhR) agonist (Ki = 3 nM). Decreases Oct4 levels in U87 glioblastoma cells. Induces stem-like cancer cell differentiation in U87 tumor spheres and inhibits ovarian cancer cell proliferation in vitro. Suppresses tumor growth in U87 and OVCAR-3 cell xenografts in mice. Also inhibits TGF-β-induced human myofibroblast differentiation.

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Quantity 10mg
Formula Weight 286.3
Percent Purity >98%
Chemical Name or Material ITE

Safety and Handling

Recommended Storage : Store at Room Temperature