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Tocris Bioscience™ IU1-47
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Quantity:
50 mg
Description
IU1-47 is a potent USP14 inhibitor (IC50 = 60 nM). Demonstrates >30-fold selectivity for USP14 over USP5 (IsoT). Enhances degradation of proteasome substrates in vitro. Increases degradation of wild type and pathological tau in MEFs, primary neuronal cultures and human iPSC derived neurons.
Specifications
Specifications
Chemical Name or Material | 1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone |
CAS | 670270-31-2 |
Quantity | 50 mg |
Molecular Formula | C19H23ClN2O |
Formula Weight | 330.85 |
Purity | 98% |
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