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Tocris™ IWP 12

Potent PORCN inhibitor; active in vivo

Manufacturer:  Tocris™ 5279/10

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Catalog No. 52-791-0


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Disclaimers:

For Research Use Only


Specifications

Description

Potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (IC50 = 15nM). Inhibits Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways. Blocks zebrafish tailfin regeneration in vivo.
  • Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]acetamide
  • Formula: C18H18N4O2S3
  • CAS Number: 688353-45-9
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

IWP 12
>98
10mg
IWP 12
418.56
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