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J 113863, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
1mg
10mg
50mg
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353791-85-2
C30H37Cl2IN2O2
655.442
FOAFBMYSXIGAOX-UHFFFAOYSA-N
1-cyclooct-1-en-1-yl methyl-4-2,7-dichloro-9h-xanthene-9-carbonyl amino-1-ethylpiperidin-1-ium iodide
70296607
2,7-dichloro-N-[1-(cycloocten-1-ylmethyl)-1-ethylpiperidin-1-ium-4-yl]-9H-xanthene-9-carboxamide;iodide
CC[N+]1(CCC(CC1)NC(=O)C2C3=C(C=CC(=C3)Cl)OC4=C2C=C(C=C4)Cl)CC5=CCCCCCC5.[I-]
This item is not returnable. View return policy
353791-85-2
C30H37Cl2IN2O2
655.442
FOAFBMYSXIGAOX-UHFFFAOYSA-N
1-cyclooct-1-en-1-yl methyl-4-2,7-dichloro-9h-xanthene-9-carbonyl amino-1-ethylpiperidin-1-ium iodide
70296607
2,7-dichloro-N-[1-(cycloocten-1-ylmethyl)-1-ethylpiperidin-1-ium-4-yl]-9H-xanthene-9-carboxamide;iodide
CC[N+]1(CCC(CC1)NC(=O)C2C3=C(C=CC(=C3)Cl)OC4=C2C=C(C=C4)Cl)CC5=CCCCCCC5.[I-]

Potent CCR1 chemokine receptor antagonist

Potent chemokine receptor 1 (CCR1) antagonist (IC 50 values are 0.9 and 5.8 nM for human and mouse CCR1 receptors respectively). Also displays high selectivity for human but not mouse CCR3 receptors (IC 50 values are 0.58 and 460 nM respectively). Improves paw inflammation, joint damage and dramatically reduces cell infiltration into joints in collagen-induced arthritis in mice. Isomer also available.

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Quantity 10mg
Formula Weight 655.44
Percent Purity >98%
Chemical Name or Material J 113863

Recommended Storage : Store at +4°C