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JAKMIP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. p-7205975 Shop All Proteintech Group Inc Products
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50-172-9040 150 μL
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Catalog No. 50-172-9040 Supplier Proteintech Group Inc Supplier No. 138461AP150UL
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Description

Rabbit Polyclonal Antibody

JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predomitly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.

Specifications

Antigen JAKMIP1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene JAKMIP1
Gene Accession No. Q8BVL9, Q96N16
Gene Alias Gababrbp, JAKMIP1, JAMIP1, Marlin 1, MARLIN1
Gene Symbols Jakmip1
Host Species Rabbit
Immunogen JAKMIP1 Fusion Protein Ag4816
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 152789, 76071
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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