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Jasplakinolide, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
100μg
This item is not returnable. View return policy
102396-24-7
C36H45BrN4O6
709.682
GQWYWHOHRVVHAP-JFKHFEEVSA-N
jasplakinolide
131843168
(4R,7R,10S,13S,15E,17R,19R)-7-[(2-bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone
CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C
This item is not returnable. View return policy
102396-24-7
C36H45BrN4O6
709.682
GQWYWHOHRVVHAP-JFKHFEEVSA-N
jasplakinolide
131843168
(4R,7R,10S,13S,15E,17R,19R)-7-[(2-bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone
CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C

Stabilizes F-actin; promotes actin polymerization

Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro. Also induces polymerization of actin monomers into F-actin in vivo. Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (K d ~ 15 nM). Exhibits antifungal and antiproliferative effects (IC 50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable.

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Quantity 100μg
Formula Weight 709.67
Percent Purity >97%
Chemical Name or Material Jasplakinolide

Recommended Storage : Store at -20°C