Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ JNJ 16259685

Tocris Bioscience™ JNJ 16259685
GREENER_CHOICE

Catalog No. 233310
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly potent, mGlu1-selective non-competitive antagonist

Sub-nanomolar potent, non-competitive mGlu1 antagonist (Ki = 0.34 nM). Inhibits glutamate-induced Ca2+ response at the human mGlu1 receptor with an IC50 value of 0.55 nM. Selective over mGlu5 (> 400-fold) and displays no activity at mGlu2, mGlu3, mGlu4, mGlu6, AMPA or NMDA receptors (IC50 > 10 μM). Centrally active following systemic administration.

Chemical Identifiers

CAS 409345-29-5
Molecular Formula C20H23NO3

Specifications

Quantity 10 mg
Formula Weight 325.41
Purity >98%
Molecular Weight (g/mol) 325.408
Chemical Name or Material JNJ 16259685

Safety and Handling

Recommended Storage Store at +4°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.