Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ JZL 184

Tocris Bioscience™ JZL 184
GREENER_CHOICE

Catalog No. 383610
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
38-361-0 10 mg
38-365-0 50 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 38-361-0 Supplier Tocris Bioscience™ Supplier No. 3836/10
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Potent MAGL inhibitor

Potent and selective MAGL inhibitor. Blocks hydrolysis of the endocannabinoid 2-arachidonyl glycerol (2-AG) in vivo in the mouse brain (IC50 = 8 nM). Potentiates depolarization-induced suppression of excitability in cerebellar Purkinje neurons. Exhibits >300-fold selectivity for MAGL over FAAH in vitro. Attenuates nociception in neuropathic and inflammatory pain models. Also reduces free fatty acid levels in primary tumors.

Chemical Identifiers

CAS 1101854-58-3
Molecular Formula C27H24N2O9

Specifications

Quantity 10 mg
Formula Weight 520.49
Purity >98%
Molecular Weight (g/mol) 520.494
Chemical Name or Material JZL 184

Safety and Handling

Recommended Storage Store at -20°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.