Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Tocris Bioscience™ Kainic acid
Click to view available options
Quantity:
1 mg
10 mg
50 mg
Description
Kainic acid, also known as kainate, is a selective agonist of kainate ionotropic glutamate receptors (EC50 = 0.6 - 7.4 μM) and a partial agonist at AMPA receptors (EC50 = 31 μM - 170 μM). Kainic acid is used to model epilepsy in vivo and to study the mechanisms of neurodegeneration and neurocytosis induced by excess stimulation by kainic acid. Kainate is shown to be involved in amyloidogenic processing of amyloid precursor protein and Aβ peptides in Alzheimer's disease.
Related compounds include synthetic Kainic acid (Cat. No. 7065), the kainate receptor agonist Domoic acid (Cat. No. 0269) and the antagonist NBQX (Cat. No. 0373).
Specifications
Specifications
Chemical Name or Material | (2 S,3 S,4 S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid |
CAS | 487-79-6 |
Assay Percent Range | >98% |
Quantity | 10 mg |
Solubility | Soluble to 25mM in water with gentle warming |
Target | Kainate Receptor Agonists |
Molecular Formula | C10H15NO4 |
Formula Weight | Observed MW: 213.23 |
Purity | 98% |
For Research Use Only
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction