Kallikrein 3/PSA Antibody (1A7) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2479680.2MG

Catalog No. NBP247968B

Description

Kallikrein 3/PSA Monoclonal antibody specifically detects Antigen in Feline, Human samples. It is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin).

Specifications

• Antigen: Kallikrein 3/PSA
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
• Gene Alias: APS seminin, EC 3.4.21, EC 3.4.21.77, Gamma-seminoprotein, hK3, kallikrein 3, (prostate specific antigen), Kallikrein-3, kallikrein-related peptidase 3, KLK2A1, P-30 antigen, prostate specific antigen, prostate-specific antigen, PSA, PSA semenogelase, Semenogelase, Seminin
• Host Species: Mouse
• Molecular Weight of Antigen: 33.5 kDa
• Quantity: 0.2 mg
• Research Discipline: Cancer, Cellular Markers, Prostate Cancer, Tumor Biomarkers
• Gene ID (Entrez): 354
• Target Species: Human, Feline
• Form: Purified

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
• Clone: 1A7 (same as 1A7G6B6)
• Conjugate: Unconjugated
• Formulation: PBS with No Preservative
• Gene Symbols: KLK3
• Immunogen: PSA (p30) from human sperm plasma
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1 κ