Kallikrein 3/PSA Antibody (1A7) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP247968A	Novus Biologicals NBP2479680.1MG	0.1 mg
NBP247968B	Novus Biologicals NBP2479680.2MG	0.2 mg

Description

Kallikrein 3/PSA Monoclonal specifically detects Kallikrein 3/PSA in Human, Feline samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.

Specifications

• Antigen: Kallikrein 3/PSA
• Concentration: 1.0 mg/mL
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Cancer, Cellular Markers, Prostate Cancer, Tumor Biomarkers
• Formulation: PBS with No Preservative
• Gene ID (Entrez): 354
• Immunogen: PSA (p30) from human sperm plasma
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Molecular Weight of Antigen: 33.5 kDa

• Clone: 1A7 (same as 1A7G6B6)
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Feline
• Gene Alias: APS seminin, EC 3.4.21, EC 3.4.21.77, Gamma-seminoprotein, hK3, kallikrein 3, (prostate specific antigen), Kallikrein-3, kallikrein-related peptidase 3, KLK2A1, P-30 antigen, prostate specific antigen, prostate-specific antigen, PSA, PSA semenogelase, Semenogelase, Seminin
• Gene Symbols: KLK3
• Isotype: IgG1 κ
• Purification Method: Protein A or G purified
• Test Specificity: Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.