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Kallikrein 3/PSA Antibody (KLK3/1248) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248333 Shop All R&D Systems Products
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NBP248333 7 mL
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Catalog No. NBP248333 Supplier Novus Biologicals Supplier No. NBP248333
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Description

Mouse Monoclonal Antibody

Kallikrein 3/PSA Monoclonal specifically detects Kallikrein 3/PSA in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Kallikrein 3/PSA
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone KLK3/1248
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias APS seminin, EC 3.4.21, EC 3.4.21.77, Gamma-seminoprotein, hK3, kallikrein 3, (prostate specific antigen), Kallikrein-3, kallikrein-related peptidase 3, KLK2A1, P-30 antigen, prostate specific antigen, prostate-specific antigen, PSA, PSA semenogelase, Semenogelase, Seminin
Gene Symbols KLK3
Host Species Mouse
Immunogen Recombinant full-length human Kallikrein 3/PSA protein (Uniprot: P07288)
Molecular Weight of Antigen 33.5 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Cancer, Cellular Markers, Prostate Cancer, Tumor Biomarkers
Primary or Secondary Primary
Gene ID (Entrez) 354
Test Specificity Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This monoclonal antibody is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This monoclonal antibody makes an excellent pair with monoclonal antibody A67-B/E3 for PSA tests.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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