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Kappa Light Chain Antibody (HP6053), Novus Biologicals™
SDP

Catalog No. NBP234257A Shop All R&D Systems Products
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0.1 mg
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Catalog No. Quantity
NBP234257A 0.1 mg
NBP234257F 0.02 mg
NBP234257B 0.2 mg
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Catalog No. NBP234257A Supplier Novus Biologicals Supplier No. NBP2342570.1MG
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Description

Mouse Monoclonal Antibody

Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Kappa Light Chain
Applications Western Blot, Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone HP6053
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-2.0ug/million cells, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P01601
Gene Alias HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Gene Symbols IGKC
Host Species Mouse
Immunogen Purified human Ig kappa chain
Molecular Weight of Antigen 22.5 kDa
Purification Method Protein A purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 3514
Test Specificity This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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