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Kappa Light Chain Antibody (KLC709), Novus Biologicals™
SDP

Catalog No. NBP234259B Shop All R&D Systems Products
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0.1 mg
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Catalog No. Quantity
NBP234259B 0.2 mg
NBP234259F 0.02 mg
NBP234259A 0.1 mg
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Catalog No. NBP234259B Supplier Novus Biologicals Supplier No. NBP2342590.2MG

Description

Mouse Monoclonal Antibody

Kappa Light Chain Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunohistochemistry (Frozen), Simple Western.

Specifications

Antigen Kappa Light Chain
Applications Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone KLC709
Conjugate Unconjugated
Dilution Simple Western 10 ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 0.5-1ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P01601
Gene Alias HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Gene Symbols IGKC
Host Species Mouse
Immunogen Recombinant human Ig kappa chain
Molecular Weight of Antigen 22.5 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 3514
Test Specificity This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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