Kappa Light Chain Antibody (L1C1), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2151910.1MG

Catalog No. NBP21519101

Description

Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples. It is validated for Western Blot, Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Kappa Light Chain
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-2ug/million cells, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page
• Gene Accession No.: P01601
• Gene Symbols: IGKC
• Immunogen: B lymphoma cells
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 3514
• Target Species: Human
• Form: Purified

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: L1C1
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
• Host Species: Mouse
• Molecular Weight of Antigen: 22.5 kDa
• Quantity: 0.1 mg
• Primary or Secondary: Primary
• Test Specificity: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

For Research Use Only