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Tocris Bioscience™ KC7F2

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Quantity:
10 mg
50 mg
Description
Inhibitor of HIF-1α. Thought to act via down-regulation of HIF-1α protein synthesis; reduces phosphorylation of eIF4E binding protein 1 (4EBP1) and p70 S6K in hypoxic conditions. Also blocks hypoxia-induced HIF-1α accumulation in a range of human cancer cell lines. Inhibits the expression of HIF target genes, such as carbonic anhydrase IX and MMP2.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 570.38 |
Purity | >98% |
Molecular Weight (g/mol) | 570.354 |
Chemical Name or Material | KC7F2 |
Safety and Handling
Recommended Storage | Store at -20°C |
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