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Tocris Bioscience™ KC7F2
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Catalog No. 432450
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Catalog No. Quantity
43-245-0 50 mg
43-241-0 10 mg
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Catalog No. 43-245-0 Supplier Tocris Bioscience™ Supplier No. 4324/50
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Description

HIF-1α inhibitor; down-regulates HIF-1α protein synthesis

Inhibitor of HIF-1α. Thought to act via down-regulation of HIF-1α protein synthesis; reduces phosphorylation of eIF4E binding protein 1 (4EBP1) and p70 S6K in hypoxic conditions. Also blocks hypoxia-induced HIF-1α accumulation in a range of human cancer cell lines. Inhibits the expression of HIF target genes, such as carbonic anhydrase IX and MMP2.

Chemical Identifiers

CAS 927822-86-4
Molecular Formula C16H16Cl4N2O4S4

Specifications

Quantity 50 mg
Formula Weight 570.38
Purity >98%
Molecular Weight (g/mol) 570.354
Chemical Name or Material KC7F2

Safety and Handling

Recommended Storage Store at -20°C
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