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KIF1B Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501559130
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50-155-9130 20 μL
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Catalog No. 50-155-9130 Supplier Bethyl Laboratories, Inc Supplier No. A301055AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.

Specifications

Antigen KIF1B
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene KIF1B
Gene Accession No. O60333, Q60575
Gene Alias Kinesin-like protein KIF1B; Klp; KIF1B; KIAA0591; KIAA1448
Gene Symbols Kif1b
Host Species Rabbit
Immunogen Between 1575 and 1625
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16561, 23095
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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