KIF1B Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-155-9130	Bethyl Laboratories, Inc A301055AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.

Specifications

• Antigen: KIF1B
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: Kinesin-like protein KIF1B; Klp; KIF1B; KIAA0591; KIAA1448
• Immunogen: Between 1575 and 1625
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: KIF1B

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: O60333, Q60575
• Gene ID (Entrez): 16561, 23095
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody