KMT2D Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-5625	Proteintech Group Inc 272661AP150UL	150 μL

Description

KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chromatin silencing, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congenital mental retardation syndrome.

Specifications

• Antigen: KMT2D
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: O14686
• Gene ID (Entrez): 8085
• Immunogen: KMT2D Fusion Protein Ag26195
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: KMT2D

• Concentration: 0.43 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: AAD10, ALL1 related protein, ALR, CAGL114, KMT2B, KMT2D, Lysine N methyltransferase 2B, MLL2, MLL4, TNRC21
• Gene Symbols: KMT2D
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody