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Tocris Bioscience™ Ko 143
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Catalog No. 324110
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective BCRP inhibitor

Potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Displays > 200-fold selectivity over P-gp and MRP-1 transporters. Increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance. Inhibits ABCB1 and ABCC1 at higher concentrations. Rapidly metabolized in rat plasma.

Chemical Identifiers

CAS 461054-93-3
Molecular Formula C26H35N3O5

Specifications

Quantity 10 mg
Formula Weight 469.57
Purity >99%
Molecular Weight (g/mol) 469.58
Chemical Name or Material Ko 143

Safety and Handling

Recommended Storage Store at -20°C
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