Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ Ko 143

Tocris Bioscience™ Ko 143
GREENER_CHOICE

Catalog No. 324110
Change view
Click to view available options
Quantity:
1 mg
10 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
32-411-0 10 mg
32-411 1 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 32-411-0 Supplier Tocris Bioscience™ Supplier No. 3241/10
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Potent and selective BCRP inhibitor

Potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Displays > 200-fold selectivity over P-gp and MRP-1 transporters. Increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance. Inhibits ABCB1 and ABCC1 at higher concentrations. Rapidly metabolized in rat plasma.

Chemical Identifiers

CAS 461054-93-3
Molecular Formula C26H35N3O5

Specifications

Quantity 10 mg
Formula Weight 469.57
Purity >99%
Molecular Weight (g/mol) 469.58
Chemical Name or Material Ko 143

Safety and Handling

Recommended Storage Store at -20°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.