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KT 5720, Tocris Bioscience™
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Catalog No. 1288100U
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Quantity:
100 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective protein kinase A inhibitor

Potent, selective inhibitor of protein kinase A (Ki = 60 nM). Has no effect on PKG or PKC (Ki > 2 μM). Reversibly arrests human skin fibroblasts in the G1 phase.

Chemical Identifiers

CAS 108068-98-0
Molecular Formula C32H31N3O5
Molecular Weight (g/mol) 537.62
MDL Number MFCD00132118,MFCD11867896
InChI Key ZHEHVZXPFVXKEY-RUAOOFDTSA-N
Synonym unii-58hv29i28s, insolution kt5720, 9r,10s,12s-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid hexyl ester, 9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, hexyl ester, 9r,10r,12s-rel, ambotzls-1036, antibiotic kt 5720, 9s,10s,12r-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid hexyl ester, 9,12-epoxy-1h-diindolo 1,2,3-fg:3',2',1'-kl pyrrolo 3,4-i 1,6 benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, hexyl ester, 9alpha,10beta,12alpha, hexyl hydroxy-methyl-oxo-? carboxylate
PubChem CID 454202
ChEBI CHEBI:85085
IUPAC Name hexyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),7(27),8(13),9,11,20,22,24-nonaene-16-carboxylate
SMILES CCCCCCOC(=O)[C@]1(O)C[C@@H]2O[C@@]1(C)N1C3=C(C=CC=C3)C3=C1C1=C(C4=CC=CC=C4N21)C1=C3CNC1=O

Specifications

Quantity 100 μg
Formula Weight 537.61
Percent Purity >98%
Chemical Name or Material KT 5720

Safety and Handling

Recommended Storage Desiccate at -20°C
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