Invitrogen™ KV4.1 (KCND1) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595216

Catalog No. PIPA595216

Description

Human KCND1 shares 90% amino acid (aa) sequence identity with mouse KCND1. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Mouse Brain Tissue, HELA whole cell, COLO320 whole cell, A549 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1. 1, KV1. 2 and KV1. 4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.

Specifications

• Antigen: KV4.1 (KCND1)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Kcnd1
• Gene Alias: 1110037K09Rik; Kca2-1; Kcnd1; KV4.1; mShal; mShal1; potassium channel, voltage gated Shal related subfamily D, member 1; potassium channel, voltage gated Shal-related subfamily D, member 1; potassium voltage gated channel Shal-related family member 1; potassium voltage gated channel, Shal-related family, member 1; potassium voltage-gated channel subfamily D member 1; potassium voltage-gated channel, Shal-related family, member 1; potassium voltage-gated channel, Shal-related subfamily, member 1; Shal; Shal1; Shal-type potassium channel; Voltage-gated potassium channel subunit Kv4.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16506, 3750
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: Q03719, Q9NSA2
• Gene Symbols: Kcnd1
• Immunogen: E.coli-derived human KCND1 recombinant protein (Position: T442-L647).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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