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Tocris Bioscience™ L-748,337
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Catalog No. 276050 Shop All Novus Biologicals Products
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Catalog No. Quantity
27-605-0 50 mg
27-601-0 10 mg
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Catalog No. 27-605-0 Supplier Tocris Bioscience™ Supplier No. 2760/50
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Description

Selective β3 antagonist

Competitive β3-adrenoceptor antagonist that displays selectivity over β1 and β2 receptors (Ki values are 4.0, 204 and 390 nM for β3-, β2- and β1-adrenoceptors respectively). Inhibits cAMP accumulation in response to isoproterenol (IC50 = 6 nM). Reduces iNOS expression, attenuates nitric oxide-induced cell proliferation and induces apoptosis in a melanoma cell line.

Chemical Identifiers

CAS 244192-94-7
Molecular Formula C26H31N3O5S

Specifications

Quantity 50 mg
Formula Weight 497.61
Purity >98%
Molecular Weight (g/mol) 497.61
Chemical Name or Material L-748, 337

Safety and Handling

Recommended Storage Store at +4°C
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