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L1CAM Mouse anti-Human, Clone: UJ127, Novus Biologicals™
SDP

Catalog No. NBP234273A Shop All R&D Systems Products
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NBP234273A 0.1 mg
NBP234273B 0.2 mg
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Catalog No. NBP234273A Supplier Novus Biologicals Supplier No. NBP2342730.1MG

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Mouse Monoclonal Antibody

L1CAM Monoclonal specifically detects L1CAM in Human samples. It is validated for Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Intracellular).

Specifications

Antigen L1CAM
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone UJ127
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen 1-2ug/ml, SDS-Page
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P32004
Gene Alias antigen identified by monoclonal R1, CAML1N-CAML1, CD171, CD171 antigen, HSAS, HSAS1, L1 cell adhesion molecule, MASA, MIC5, N-CAM-L1, NCAM-L1, neural cell adhesion molecule L1, S10, SPG1
Gene Symbols L1CAM
Host Species Mouse
Immunogen Homogenous suspension of 16 week human fetal brain
Molecular Weight of Antigen 230 kDa
Purification Method Protein A purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cellular Markers, Glia Markers, Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) 3897
Test Specificity Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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