Epredia™ Lab Vision™ COX2 Rabbit Polyclonal Antibody with BSA and azide

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Epredia™ COX2, Rabbit Polyclonal Antibody.

Catalog Number	Mfr. No.	Form	Quantity
RB9072P1	Epredia™ RB9072P1	Concentrated	500 μL
RB9072P	Epredia™ RB9072P	Concentrated	1 mL
RB9072R1	Epredia™ RB9072R1	Prediluted	1 mL
RB9072R7	Epredia™ RB9072R7	Prediluted	7 mL

Description

COX2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate-early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, and Rat. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide corresponding to C-terminus of rat COX2

Molecular Weight: 70 kDa

Positive Control: HT29 cells, Lung and colon CA

Cellular Localization: Cytoplasmic and membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation

Specifications

• Antigen: COX2
• Classification: Polyclonal
• Host Species: Rabbit
• Research Discipline: Enzyme
• Immunogen: Synthetic peptide corresponding to c-terminus of rat COX2
• Primary or Secondary: Primary

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Regulatory Status: IVD
• Target Species: Human, Mouse
• Isotype: IgG