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Cyclin D1 Rabbit Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cyclin D1, Rabbit Monoclonal Antibody.

Specifications

Antigen Cyclin D1
Clone EPR2241IHC
Applications Immunohistochemistry
Conjugate Unconjugated
Host Species Rabbit
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Products 3
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
RM2113R1
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Epredia
RM2113R1
Ready-to-Use 1 mL N/A N/A N/A
RM2113R7
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Epredia
RM2113R7
Ready-to-Use 7 mL N/A N/A N/A
RM2113RQ
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Epredia
RM2113RQ
Ready-to-Use 12 mL N/A N/A N/A
Description

Description

Cyclin D1 or PRAD-1 or bcl-1 is a key cell cycle regulator. It functions in association with cdk4 and/or cdk6 by phosphorylating the retinoblastoma protein that releases transcription factors to initiate DNA replication. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. In lymphoid lesions, with the exception of few rare diseases, it is specific for mantle cell lymphoma (MCL).

Host Species: Rabbit

Clone: EPR2241IHC

Isotype: IgG

Species Reactivity: Human. Others not tested.

Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1

Molecular Weight: 36 kDa

Positive Control: Mantle cell lymphoma

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Specifications

Cyclin D1
Immunohistochemistry
Rabbit
Primary
EPR2241IHC
Unconjugated
A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1
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