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Epredia™ Lab Vision™ Ku (p70/p80) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Recommended for multiple molecular biology techniques, Epredia™ Ku (p70/p80) Ab-3, Mouse Monoclonal Antibody provides accurate, reproducible results.
Specifications
| Antigen | Ku (p70/p80) Ab-3 |
|---|---|
| Clone | 162 |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin) |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
|
MS286R1
|
Epredia™
MS286R1 |
Prediluted | 1 mL | N/A | N/A | N/A | |||
Description
The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.Host Species: Mouse
Clone: 162
Isotype: IgG2a
Species Reactivity: Human, Monkey, Xenopus. Mouse and Rat (Immunoprecipitation only). Does not react with cow and rabbit.
Epitope: A conformational epitope of p70/p80 dimer, which is destroyed during Western Blotting
Immunogen: Human B-cell nuclei from plasmacytoid 2p68 cells
Molecular Weight: 70kDa and 80kDa
Positive Control: Tonsil
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting (Not suitable)
- Immunofluorescence
- Affinity Purification
- Flow Cytometry
- Gel Supershift
1. Wang J, et. al. Molecular Biology Reports, 1993, 18(1):15-28.
2. Reeves WH, et. al. Journal of Experimental Medicine, 1985, 161(1):18-39.
Specifications
| Ku (p70/p80) Ab-3 | |
| Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| RUO | |
| Human, Non-human Primate, Xenopus species | |
| IgG2a |
| 162 | |
| Monoclonal | |
| Mouse | |
| DNA Repair | |
| Human B cell nuclei from plasmacytoid 2p68 cells | |
| Primary |
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