Epredia™ Lab Vision™ NFκB/p65 (Rel A) Ab-1 Rabbit Polyclonal Antibody with BSA and azide

Epredia™ NFκB/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia™ RB1638R1

Catalog No. RB1638R1

Description

NFκ B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA). The p50/p65 heterodimer is present in the cytoplasm in inactive form bound to its inhibitor, IdeltaB. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFκB which goes to the nucleus inducing gene expression. NFκB was originally identified as transcriptional activator for kappa light chain gene in B cells.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drosophila, Xenopus. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of human NFκB protein

Molecular Weight: 65kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: NFkappaB/p65 (Rel A) Ab-1
• Classification: Polyclonal
• Formulation: Ready-to-use for IHC (UVLP)
• Immunogen: A synthetic peptide from the C-terminus of human NFkappaB protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Prediluted

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Quantity: 1 mL
• Research Discipline: Transcription Regulation
• Target Species: Bovine, Canine, Drosophila, Hamster, Human, Mouse, Pig, Rabbit, Rat
• Isotype: IgG