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  6. Epredia™ Lab Vision™ NFκB/p65 (Rel A) Ab-1 Rabbit Polyclonal Antibody with BSA and azide

Epredia™ Lab Vision™ NFκB/p65 (Rel A) Ab-1 Rabbit Polyclonal Antibody with BSA and azide

Epredia™ NFκB/p65 (Rel A) Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.

Specifications

Antigen NFkappaB/p65 (Rel A) Ab-1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Host Species Rabbit
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Products 1
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
RB1638R1
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Epredia™
RB1638R1 		Prediluted 1 mL N/A N/A N/A
Description

Description

NFκ B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA). The p50/p65 heterodimer is present in the cytoplasm in inactive form bound to its inhibitor, IdeltaB. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFκB which goes to the nucleus inducing gene expression. NFκB was originally identified as transcriptional activator for kappa light chain gene in B cells.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drosophila, Xenopus. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of human NFκB protein

Molecular Weight: 65kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

NFkappaB/p65 (Rel A) Ab-1
Polyclonal
Rabbit
Transcription Regulation
IgG
Western Blot
Unconjugated
RUO
A synthetic peptide from the C-terminus of human NFkappaB protein
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