Epredia™ Lab Vision™ Prostate Specific Membrane Antigen (PSMA) Rabbit Monoclonal Antibody, supernatant

Employ part of a comprehensive antibody portfolio with the Epredia™ Prostate Specific Membrane Antigen, Rabbit Monoclonal Antibody. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Catalog Number	Mfr. No.	Form	Quantity
RM9131S0	Epredia™ RM9131S0	Concentrated	100 μL
RM9131S	Epredia™ RM9131S	Concentrated	1 mL
RM9131R1	Epredia™ RM9131R1	Prediluted	1 mL
RM9131R7	Epredia™ RM9131R7	Prediluted	7 mL
RM9131RQ	Epredia™ RM9131RQ	Ready-to-Use	12 mL

Description

Prostate Specific Membrane Antigen (PSMA) is a surface glycoprotein with restricted expression to normal prostate tissue, primary and metastatic prostate cancer and the neovasculature of various nonprostatic epithelial malignancies. Overexpression of PSMA is correlated with high tumor grade, non-diploid tumors, and advanced tumor stage. Even though PSA is useful in identifying the prostate origin of cancers, PSMA shows moderate to strong positivity in one-half of the cells per case that show relatively poor PSA staining, and is excellent in differentiating between prostatic adenocarcinoma and urothelial carcinoma. PSMA is expressed in 94.3% to 100% of primary and 57.7% to 100% of metastatic prostatic carcinomas. PSMA is recognized as a viable target for cancer therapy.

Host Species: Rabbit

Clone: SP29

Species Reactivity: Human. Others not known.

Immunogen: C-terminal

Molecular Weight: 84kDa

Positive Control: Prostate carcinoma

Cellular Localization: Cytoplasmic and membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: Prostate Specific Membrane Antigen (PMSA)
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Regulatory Status: IVD
• Immunogen: C-terminal

• Clone: SP29
• Classification: Monoclonal
• Host Species: Rabbit
• Research Discipline: Cancer and Tumor Biology
• Primary or Secondary: Primary