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Epredia™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2 Rat Monoclonal Antibody with BSA and azide
Provide accurate, reproducible results with the Epredia™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.
Specifications
| Antigen | Raf-1 (Phospho-specific) Ab-2 |
|---|---|
| Clone | pS338[DPR/2/2A/3A] |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
|
RT1732R1
|
Epredia™
RT1732R1 |
Prediluted | 1 mL | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | ||||
Description
Raf1 is an important mediator of signal transduction pathway. It is activated through activation by Src and protein kinase C. It further phosphorylates Mek1 and cdc25. It can bind to GTP-bound Ras through N-terminal domain. It also interacts with hsp90 and 14.3.3 family of proteins.Host Species: Rat
Clone: pS338[DPR/2/2A/3A]
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: GQRDS™SYY™WEIEAS
Immunogen: A synthetic peptide corresponding to aa GQRDS™SYY™WEIEAS
Molecular Weight: 74kDa
Positive Control: Tonsil
Cellular Localization: Nuclear Ab-2 binds to phosphorylated serine residue at aa338. It does not bind to unactivated Raf-1 or Raf-1 phosphorylated at Y341 and S339.
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Note:
USA: RUO; Int'l: RUO
General References:
1. Mason C S, et al. (1999) EMBO J, 18:2137-2148.
Specifications
| Raf-1 (Phospho-specific) Ab-2 | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| RUO | |
| Human | |
| IgG1 |
| pS338[DPR/2/2A/3A] | |
| Monoclonal | |
| Rat | |
| Signal Transduction | |
| A synthetic peptide corresponding to aa GQRDSasteriskSYYasteriskWEIEAS | |
| Primary |
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