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Epredia™ Lab Vision™ Retinoblastoma (Rb) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, biotinylated, BSA and azide

Provide accurate, reproducible results with the Epredia™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody.

$399.00 - $664.00

Specifications

Antigen Retinoblastoma (Rb) Ab-1
Clone 1F8; same as Rb1
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Host Species Mouse
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Products 9
Catalog Number Mfr. No. Form Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Conjugate Quantity Price Quantity & Availability  
MS107P1ABX
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Epredia™
MS107P1ABX
Concentrated Unconjugated 100 μL
Each for $664.00
Only null left
Add to Cart
 
MS107P1
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Epredia™
MS107P1
Concentrated Unconjugated 500 μL
Each for $646.00
Only null left
Add to Cart
 
MS107R7
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Epredia™
MS107R7
Prediluted Unconjugated 7 mL
Each for $399.00
Only null left
Add to Cart
 
MS107B0
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Epredia™
MS107B0
Concentrated Biotin 100 μL N/A N/A N/A
MS107B1
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Epredia™
MS107B1
Concentrated Biotin 500 μL N/A N/A N/A
MS107B
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Epredia™
MS107B
Concentrated Biotin 1 mL N/A N/A N/A
MS107P0
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Epredia™
MS107P0
Concentrated Unconjugated 100 μL N/A N/A N/A
MS107PABX
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Epredia™
MS107PABX
Concentrated Unconjugated 200 μL N/A N/A N/A
MS107R1
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Epredia™
MS107R1
Prediluted Unconjugated 1 mL N/A N/A N/A
Description

Description

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Host Species: Mouse

Clone: 1F8; same as Rb1

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: aa 703-722

Immunogen: Recombinant human Rb protein

Molecular Weight: 105kDa

Positive Control: Ls174T, HT29, HUVEC cells; Normal colon, Breast CA and colon CA

Cellular Localization: Nuclear Ab-1 specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It reacts with hyperphosphorylated and un (under) phosphorylated form of Rb protein. It shows no cross reaction with p107 and p130.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Retinoblastoma (Rb) Ab-1
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Mouse
Cancer and Tumor Biology
Recombinant human Rb protein
Primary
1F8; same as Rb1
Monoclonal
RUO
Human
IgG1
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Documents

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