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Tubulin-α Ab-2 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Tubulin-α Ab-2, Mouse Monoclonal Antibody.

$299.50 - $1211.00

Specifications

Antigen Tubulin, alpha Ab-2
Clone DM1A
Applications Immunoassay, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 7
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Quantity Price Quantity & Availability  
MS581P0
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Epredia
MS581P0
Concentrated 100 μL
Each for $299.50
Only null left
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MS581PABX
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Epredia
MS581PABX
Concentrated 200 μL
Each for $1,178.00
Only null left
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MS581P1
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Epredia
MS581P1
Concentrated 500 μL
Each for $749.00
Only null left
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MS581P
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Epredia
MS581P
Concentrated 1 mL
Each for $1,211.00
Only null left
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MS581P1ABX
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Epredia
MS581P1ABX
Concentrated 100 μL N/A N/A N/A
MS581R1
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Epredia
MS581R1
Prediluted 1 mL N/A N/A N/A
MS581R7
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Epredia
MS581R7
Prediluted 7 mL N/A N/A N/A
Description

Description

Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kDa subunits: α and Β. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton.

Host Species: Mouse

Clone: DM1A

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Pig, Rat, Mouse, Guinea Pig, Gerbil, Frog and Chicken. Others not known.

Epitope: aa 426-450

Immunogen: Native chick brain microtubules

Molecular Weight: 57kDa

Positive Control: Ls174T, MAD109 cells; skin or lung

Cellular Localization: Cytoplasmic Ab-2 causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps. It does not block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro. It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Tubulin, alpha Ab-2
Immunoassay, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RUO
Bovine, Chicken, Frog, Gerbil, Guinea Pig, Human, Mouse, Pig, Rat
IgG2a κ
DM1A
Monoclonal
Mouse
Cytoskeletal Protein
Native chick brain microtubules
Primary
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